I, a php/js web developer, have over the past few years launched and maintained a C# .NET app and can testify that the experience has been overall pretty positive as somebody that had never even launched visual studio before except for playing around unity and doing some tutorials.

And I say this even after the adventure of trying to decipher whatever Microsoft is doing/going with their 4 or 5 competing frameworks and SDKs.

But I still find huge value and love a good web app whenever what you need doesn't really need to be native which was not my case.

There will still be uses for native apps for a long time IMHO.